The food sanitizer is temporarily removed when you enter Tranquility Lane in Vault 112, when you are captured by Colonel Autumn, when you enter the Operation: Anchorage Simulator located in the Outcast Outpost, when you enter The Pitt, and when you are abducted by aliens on Mothership Zeta, along with all other non-quest items. According to the in-game dialogue, it will cleanse most food in the inventory of harmful bacteria, allowing greater nutritional gain.
The food sanitizer has no effect on the radiation rating of the food. While in the player's inventory, the food sanitizer will increase the HP value of food by 20%.
The food sanitizer in Fallout 3 has a passive effect on the player as long as it is in the player's inventory.
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